WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_V$E2F1_Q4_01       ID:DB_ID:2312
C=226; O=6; E=0.69; R=8.74; rawP=7.02e-05; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000153914 NA SREK1 splicing regulatory glutamine/lysine-rich protein 1 140890 ENSG00000153914
2  ENSG00000082258 NA CCNT2 cyclin T2 905 ENSG00000082258
3  ENSG00000186908 NA ZDHHC17 zinc finger, DHHC-type containing 17 23390 ENSG00000186908
4  ENSG00000164663 NA USP49 ubiquitin specific peptidase 49 25862 ENSG00000164663
5  ENSG00000143033 NA MTF2 metal response element binding transcription factor 2 22823 ENSG00000143033
6  ENSG00000100201 NA DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 10521 ENSG00000100201


Database:Transcription Target       Name:hsa_V$E2F1_Q6_01       ID:DB_ID:2314
C=235; O=6; E=0.71; R=8.41; rawP=8.70e-05; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143190 NA POU2F1 POU class 2 homeobox 1 5451 ENSG00000143190
2  ENSG00000153914 NA SREK1 splicing regulatory glutamine/lysine-rich protein 1 140890 ENSG00000153914
3  ENSG00000164663 NA USP49 ubiquitin specific peptidase 49 25862 ENSG00000164663
4  ENSG00000143033 NA MTF2 metal response element binding transcription factor 2 22823 ENSG00000143033
5  ENSG00000184083 NA FAM120C family with sequence similarity 120C 54954 ENSG00000184083
6  ENSG00000100201 NA DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 10521 ENSG00000100201


Database:Transcription Target       Name:hsa_TGGAAA_V$NFAT_Q4_01       ID:DB_ID:2437
C=1871; O=17; E=5.68; R=2.99; rawP=5.48e-05; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000134444 NA KIAA1468 KIAA1468 57614 ENSG00000134444
2  ENSG00000196705 NA ZNF431 zinc finger protein 431 170959 ENSG00000196705
3  ENSG00000198315 NA ZNF192 zinc finger protein 192 7745 ENSG00000198315
4  ENSG00000184083 NA FAM120C family with sequence similarity 120C 54954 ENSG00000184083
5  ENSG00000185278 NA ZBTB37 zinc finger and BTB domain containing 37 84614 ENSG00000185278
6  ENSG00000153914 NA SREK1 splicing regulatory glutamine/lysine-rich protein 1 140890 ENSG00000153914
7  ENSG00000143442 NA POGZ pogo transposable element with ZNF domain 23126 ENSG00000143442
8  ENSG00000100201 NA DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 10521 ENSG00000100201
9  ENSG00000127980 NA PEX1 peroxisomal biogenesis factor 1 5189 ENSG00000127980
10  ENSG00000181619 NA GPR135 G protein-coupled receptor 135 64582 ENSG00000181619
11  ENSG00000082258 NA CCNT2 cyclin T2 905 ENSG00000082258
12  ENSG00000147162 NA OGT O-linked N-acetylglucosamine (GlcNAc) transferase 8473 ENSG00000147162
13  ENSG00000171444 NA MCC mutated in colorectal cancers 4163 ENSG00000171444
14  ENSG00000139746 NA RBM26 RNA binding motif protein 26 64062 ENSG00000139746
15  ENSG00000156042 NA TTC18 tetratricopeptide repeat domain 18 118491 ENSG00000156042
16  ENSG00000243444 NA PALM2 paralemmin 2 114299 ENSG00000243444 ENSG00000157654
17  ENSG00000122481 NA RWDD3 RWD domain containing 3 25950 ENSG00000122481


Database:Transcription Target       Name:hsa_V$E2F_03       ID:DB_ID:2158
C=243; O=7; E=0.74; R=9.48; rawP=1.02e-05; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000082258 NA CCNT2 cyclin T2 905 ENSG00000082258
2  ENSG00000186908 NA ZDHHC17 zinc finger, DHHC-type containing 17 23390 ENSG00000186908
3  ENSG00000138658 NA C4orf21 chromosome 4 open reading frame 21 55345 ENSG00000138658
4  ENSG00000164663 NA USP49 ubiquitin specific peptidase 49 25862 ENSG00000164663
5  ENSG00000143033 NA MTF2 metal response element binding transcription factor 2 22823 ENSG00000143033
6  ENSG00000184083 NA FAM120C family with sequence similarity 120C 54954 ENSG00000184083
7  ENSG00000100201 NA DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 10521 ENSG00000100201


Database:Transcription Target       Name:hsa_RCGCANGCGY_V$NRF1_Q6       ID:DB_ID:2441
C=894; O=12; E=2.72; R=4.42; rawP=1.95e-05; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000138468 NA SENP7 SUMO1/sentrin specific peptidase 7 57337 ENSG00000138468
2  ENSG00000178567 NA EPM2AIP1 EPM2A (laforin) interacting protein 1 9852 ENSG00000178567
3  ENSG00000138658 NA C4orf21 chromosome 4 open reading frame 21 55345 ENSG00000138658
4  ENSG00000184083 NA FAM120C family with sequence similarity 120C 54954 ENSG00000184083
5  ENSG00000133226 NA SRRM1 serine/arginine repetitive matrix 1 10250 ENSG00000133226
6  ENSG00000143190 NA POU2F1 POU class 2 homeobox 1 5451 ENSG00000143190
7  ENSG00000116001 NA TIA1 TIA1 cytotoxic granule-associated RNA binding protein 7072 ENSG00000116001
8  ENSG00000138380 NA ALS2CR8 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8 79800 ENSG00000138380
9  ENSG00000164180 NA TMEM161B transmembrane protein 161B 153396 ENSG00000164180
10  ENSG00000168040 NA FADD Fas (TNFRSF6)-associated via death domain 8772 ENSG00000168040
11  ENSG00000186001 NA LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3 84859 ENSG00000186001
12  ENSG00000110047 NA EHD1 EH-domain containing 1 10938 ENSG00000110047


Database:Transcription Target       Name:hsa_V$AR_01       ID:DB_ID:2133
C=153; O=5; E=0.46; R=10.76; rawP=0.0001; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000153914 NA SREK1 splicing regulatory glutamine/lysine-rich protein 1 140890 ENSG00000153914
2  ENSG00000134444 NA KIAA1468 KIAA1468 57614 ENSG00000134444
3  ENSG00000164180 NA TMEM161B transmembrane protein 161B 153396 ENSG00000164180
4  ENSG00000115524 NA SF3B1 splicing factor 3b, subunit 1, 155kDa 23451 ENSG00000115524
5  ENSG00000090905 NA TNRC6A trinucleotide repeat containing 6A 27327 ENSG00000090905


Database:Transcription Target       Name:hsa_V$E2F_Q4_01       ID:DB_ID:2296
C=234; O=6; E=0.71; R=8.44; rawP=8.50e-05; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000153914 NA SREK1 splicing regulatory glutamine/lysine-rich protein 1 140890 ENSG00000153914
2  ENSG00000186908 NA ZDHHC17 zinc finger, DHHC-type containing 17 23390 ENSG00000186908
3  ENSG00000164663 NA USP49 ubiquitin specific peptidase 49 25862 ENSG00000164663
4  ENSG00000143033 NA MTF2 metal response element binding transcription factor 2 22823 ENSG00000143033
5  ENSG00000184083 NA FAM120C family with sequence similarity 120C 54954 ENSG00000184083
6  ENSG00000100201 NA DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 10521 ENSG00000100201


Database:Transcription Target       Name:hsa_V$CART1_01       ID:DB_ID:2083
C=220; O=6; E=0.67; R=8.98; rawP=6.05e-05; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000143190 NA POU2F1 POU class 2 homeobox 1 5451 ENSG00000143190
2  ENSG00000153914 NA SREK1 splicing regulatory glutamine/lysine-rich protein 1 140890 ENSG00000153914
3  ENSG00000095574 NA IKZF5 IKAROS family zinc finger 5 (Pegasus) 64376 ENSG00000095574
4  ENSG00000143442 NA POGZ pogo transposable element with ZNF domain 23126 ENSG00000143442
5  ENSG00000175893 NA ZDHHC21 zinc finger, DHHC-type containing 21 340481 ENSG00000175893
6  ENSG00000090905 NA TNRC6A trinucleotide repeat containing 6A 27327 ENSG00000090905


Database:Transcription Target       Name:hsa_V$E2F_Q6_01       ID:DB_ID:2297
C=239; O=6; E=0.73; R=8.26; rawP=9.54e-05; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000153914 NA SREK1 splicing regulatory glutamine/lysine-rich protein 1 140890 ENSG00000153914
2  ENSG00000186908 NA ZDHHC17 zinc finger, DHHC-type containing 17 23390 ENSG00000186908
3  ENSG00000164663 NA USP49 ubiquitin specific peptidase 49 25862 ENSG00000164663
4  ENSG00000143033 NA MTF2 metal response element binding transcription factor 2 22823 ENSG00000143033
5  ENSG00000184083 NA FAM120C family with sequence similarity 120C 54954 ENSG00000184083
6  ENSG00000100201 NA DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 10521 ENSG00000100201


Database:Transcription Target       Name:hsa_V$IRF1_Q6       ID:DB_ID:2241
C=254; O=6; E=0.77; R=7.78; rawP=0.0001; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000116001 NA TIA1 TIA1 cytotoxic granule-associated RNA binding protein 7072 ENSG00000116001
2  ENSG00000153914 NA SREK1 splicing regulatory glutamine/lysine-rich protein 1 140890 ENSG00000153914
3  ENSG00000185278 NA ZBTB37 zinc finger and BTB domain containing 37 84614 ENSG00000185278
4  ENSG00000110047 NA EHD1 EH-domain containing 1 10938 ENSG00000110047
5  ENSG00000090905 NA TNRC6A trinucleotide repeat containing 6A 27327 ENSG00000090905
6  ENSG00000100201 NA DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17 10521 ENSG00000100201




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).